| 摘要 |
<p>The invention relates to biparatopic A-beta binding polypeptides and, more specifically, to biparatopic A-beta binding polypeptides comprising at least two immunoglobulin single variable domains binding to different epitopes of A-beta. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as Alzheimer's Disease.</p> |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
PARK, JOHN E.;DORNER-CIOSSEK, CORNELIA;HOERER, STEFAN;KUSSMAUL, LOTHAR;LENTER, MARTIN;ZIMMERMANN, KATHARINA;BESTE, GERALD;LAEREMANS, TOON;MERCHIERS, PASCAL;VERCAMMEN, JO |
