| 发明名称 |
PHOSPHOROTHIOATE OLIGONUCLEOTIDES AND NON-NUCLEOSIDIC PHOSPHOROTHIOATES AS DELIVERY AGENTS FOR iRNA AGENTS |
| 摘要 |
The invention relates to use of single-stranded phosphorothioate oligonucleotides or non-nucleosidic phosphrothiaote as vehicles or carriers to modulate the biodistribution of iRNA agents.
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| 申请公布号 |
US2011218334(A1) |
申请公布日期 |
2011.09.08 |
| 申请号 |
US200913003355 |
申请日期 |
2009.07.10 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
MAIER MARTIN;MANOHARAN MUTHIAH;RAJEEV KALLANTHOTTATHIL G.;FITZGERALD KEVIN;DE FOUGEROLLES ANTONIN;NOVOBRANTSEVA TATIANE;BORODOVSKY ANNA;FRANK-KAMENETSKY MARIA |
| 分类号 |
C07H21/02;C12N15/11;C12N15/113 |
主分类号 |
C07H21/02 |
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