| 发明名称 |
ANTI-PLATELET MEMBRANE GLYCOPROTEIN VI MONOCLONAL ANTIBODY |
| 摘要 |
The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.
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| 申请公布号 |
US2011217318(A1) |
申请公布日期 |
2011.09.08 |
| 申请号 |
US201113095098 |
申请日期 |
2011.04.27 |
| 申请人 |
MOCHIDA PHARMACEUTICAL CO., LTD. |
发明人 |
TAKAYAMA HIROSHI;SHIRAKAWA KAMON;FURUSAKO SHOJI;HOSAKA YOSHITAKA;MATSUSUE TOMOKAZU;NAITOH KATSUKI;HOTTA YUMI;KAWAHARA TETSUSHI;HONDA MOTOYASU |
| 分类号 |
A61K39/395;A61P7/02;C07H21/00;C07K16/28;C07K19/00;C12N5/071;C12N15/63;C12P21/02 |
主分类号 |
A61K39/395 |
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