发明名称
摘要 Disclosed are compounds of the Formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein R 1 , R 2 , R 7 , R 8 and R 9 , W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
申请公布号 JP4768628(B2) 申请公布日期 2011.09.07
申请号 JP20060541582 申请日期 2004.11.18
申请人 发明人
分类号 C07D215/48;A01N33/02;A01N43/42;A01N43/54;A01N43/58;A01N43/60;A01N43/64;A01N43/90;A61K;A61K31/40;A61K31/415;A61K31/416;A61K31/44;A61K31/4439;A61K31/47;A61K31/4745;A61K31/495;A61K31/50;A61K31/501;A61K31/502;A61K31/517;A61K31/519;A61K31/53;A61K31/655;A61P1/04;A61P1/18;A61P3/10;A61P9/04;A61P9/10;A61P9/14;A61P11/00;A61P11/02;A61P11/06;A61P13/08;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/08;A61P25/00;A61P25/04;A61P25/06;A61P27/02;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P35/02;A61P37/00;A61P37/06;A61P37/08;A61P43/00;C07D;C07D209/44;C07D209/46;C07D213/80;C07D213/82;C07D221/04;C07D231/56;C07D237/24;C07D237/26;C07D237/28;C07D237/32;C07D239/74;C07D239/94;C07D401/04;C07D401/06;C07D403/02;C07D413/02;C07D413/04;C07D413/14;C07D417/02;C07D417/04;C07D471/02;C07D471/04;C07D487/02;C07D491/02;C07D498/02 主分类号 C07D215/48
代理机构 代理人
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