发明名称 |
PHARMACEUTICAL COMPOSITION INCLUDING TAT-HOXB4H PROTEIN FOR ENHANCING MOBILIZATION OF HEMATOPOIETIC STEM CELL FROM BONE MARROW TO PERIPHERAL BLOOD, AND PHARMACEUTICAL COMPOSITION FOR IMPROVING RECOVERY TIME OF PATIENT HAVING UNDERGONE HEMATOPOIETIC STEM CELL TRANSPLANTATION, IRRADIATION, OR CHEMOTHERAPY |
摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a pharmaceutical composition, including a TAT-HOXB4H protein, for enhancing mobilization of hematopoietic stem cells (HSC) from bone marrow to peripheral blood, and a pharmaceutical composition for improving the recovery time of a patient having undergone HSC transplantation, irradiation, or chemotherapy. <P>SOLUTION: The pharmaceutical composition, including the TAT-HOXB4H protein, for enhancing the mobilization of HSCs from bone marrow to peripheral blood is administered in an effective amount to a subject in need thereof, and allows the TAT-HOXB4H protein to increase the absolute number of HSCs in the bone marrow of the subject thereby enhancing the mobilization of HSCs to the peripheral blood of the subject. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
申请公布号 |
JP2011168597(A) |
申请公布日期 |
2011.09.01 |
申请号 |
JP20110062807 |
申请日期 |
2011.03.22 |
申请人 |
TAIWAN ADVANCE BIO-PHARM INC |
发明人 |
WU KOU-JUEY;HUANG CHI-HUNG |
分类号 |
A61K38/00;A61P7/00;A61P7/06;A61P35/00;A61P35/02;C07K14/47;C12N15/09;C12P21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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