发明名称 |
PROCESS |
摘要 |
PROBLEM TO BE SOLVED: To provide an individuated cancer treatment method to estimate whether a patient responds to a chemotherapeutic agent by using a marker gene set, and a kit used in the method. SOLUTION: There are provided: a set of isolated marker genes comprising at least one gene identified as having differential expression as between patients who are responders and non-responders to an erbB receptor tyrosine kinase inhibitor; the gene set comprising one or more genes selected from at least the group consisting of specific 51 genes including gene-specific oligonucleotides derived from the genes; and uses of such sets in diagnostic applications. COPYRIGHT: (C)2011,JPO&INPIT
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申请公布号 |
JP2011167188(A) |
申请公布日期 |
2011.09.01 |
申请号 |
JP20110030571 |
申请日期 |
2011.02.16 |
申请人 |
ASTRAZENECA UK LTD;UNIV OF TOKYO |
发明人 |
TSURUO TAKASHI;NAKAMURA YUSUKE;SONE SABURO;FUKUOKA MASAHIRO |
分类号 |
C12N15/09;A61K39/395;A61K45/00;A61P11/00;A61P35/00;A61P43/00;C07K14/47;C12Q1/68;G01N33/48;G01N33/53;G01N33/574;G01N37/00 |
主分类号 |
C12N15/09 |
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