发明名称 CHONDROGENESIS OF MESENCHYMAL STEM CELLS USING DKK-1 OR SFRP-1
摘要 The present invention relates to a method for inducing differentiation of cartilage cells from mesenchymal stem cells, and more particularly, to a method for inducing differentiation of cartilage cells, wherein mesenchymal stem cells are cultured in the presence of DKK-1 or sFRP-1 which serves as a wnt signal transduction inhibitor, and to a treatment composition containing cartilage cells differentiated by said method. The method for differentiating mesenchymal stem cells into cartilage cells according to the present invention uses DKK-1 or sFRP-1 treatment during the early stage of cell culture, so as to prevent differentiation into other cells during the initial cell differentiation of mesenchymal stem cells, thus obtaining cartilage cells in an easier manner.
申请公布号 WO2011065661(A3) 申请公布日期 2011.09.01
申请号 WO2010KR06837 申请日期 2010.10.06
申请人 DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;IM, GUN IL 发明人 IM, GUN IL
分类号 C12N5/07;A61F2/30;A61K35/32;C12N5/02 主分类号 C12N5/07
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