HIGHLY-EFFICIENT MANUFACTURING METHOD OF INDUCED PLURIPOTENT STEM CELLS AND INDUCED PLURIPOTENT STEM CELLS PRODUCED BY THE METHOD
摘要
The present invention relates to a method for manufacturing personalized pluripotent stem cells having the same differentiation potency as embryonic stem cells, which comprises the following steps: preparing protein extracts separated from various types of undifferentiated stem cells induced through a variety of methods (induced Pluripotent Stem cells, iPS); infusing the extracts into adult cells; and deriving pluripotent stem cells having the same differentiation potency as embryonic stem cells by culturing the adult cells infused with the extracts. In addition, the present invention relates to pluripotent stem cells produced by the method and cell therapy products that include pluripotent stem cells. In comparison to conventional manufacturing methods for pluripotent stem cells, the method of the present invention allows pluripotent stem cells to be produced with ease and remarkably high efficiency.
申请公布号
WO2011037367(A3)
申请公布日期
2011.09.01
申请号
WO2010KR06374
申请日期
2010.09.17
申请人
SEOUL NATIONAL UNIVERSITY HOSPITAL;PARK, YOUNG-BAE;KIM, HYO-SOO;KWON, YOO-WOOK;CHO, HYUN-JAI;PAEK, JAE-SEUNG
发明人
PARK, YOUNG-BAE;KIM, HYO-SOO;KWON, YOO-WOOK;CHO, HYUN-JAI;PAEK, JAE-SEUNG