| 发明名称 |
METHODS OF TREATMENT USING IL-16 ANTAGONIST PEPTIDES |
| 摘要 |
The present invention has found that a series of peptides having sequences that substantially correspond to specific regions of the C-terminus of IL-16 can inhibit the activity of IL-16. The present invention has demonstrated that such IL-16-inhibiting peptides can be as short as 4 amino acid in length. Based on these discoveries, the present invention provides IL-16 antagonist peptides and the use thereof for the treatment of IL-16 mediated disorders such as certain inflammatory diseases. |
| 申请公布号 |
US2011207679(A1) |
申请公布日期 |
2011.08.25 |
| 申请号 |
US201113030201 |
申请日期 |
2011.02.18 |
| 申请人 |
TRUSTEES OF BOSTON UNIVERSITY |
发明人 |
CENTER DAVID M.;CRUIKSHANK WILLIAM W.;KORNFELD HARDY |
| 分类号 |
A61K38/07;C12N15/09;A61K31/56;A61K38/00;A61K39/395;A61P1/00;A61P1/04;A61P5/14;A61P11/06;A61P19/02;A61P25/00;A61P25/28;A61P29/00;A61P31/22;C07H21/00;C07K5/00;C07K5/10;C07K5/11;C07K7/06;C07K7/08;C07K14/54;C07K16/18;C07K16/44 |
主分类号 |
A61K38/07 |
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