| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide certain 1-substituted-2,3,4,5-tetrahydro-3-benzazepine derivatives of formula (I), that are modulators of the 5HT<SB>2C</SB>receptor. <P>SOLUTION: Compounds of the present invention are useful for the prophylaxis or treatment of 5HT<SB>2C</SB>receptor-associated diseases, conditions, or disorders, such as obesity and related disorders. The 5HT<SB>2C</SB>receptor is a validated and well-accepted receptor target for the prophylaxis and/or treatment of 5HT<SB>2C</SB>mediated receptor diseases and disorders, such as obesity, eating disorders, psychiatric disorders, Alzheimer Disease, sexual dysfunction, and disorders related thereto. The present invention is drawn to compounds which bind to the 5HT<SB>2C</SB>receptor and modulate the activity of the 5HT<SB>2C</SB>receptor, and uses thereof. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
