AGENT IN FORM OF 8-(METHOXYCARBONYL)-4b,8-DIMETHYL-3-(2-METHYLPROPANOYL)-TETRADECAHYDROPHENANTHRENE-1,2,10a-TRICARBOXYLIC ACID AND PREPARATION METHOD THEREOF

摘要

FIELD: chemistry. ^ SUBSTANCE: invention relates to the chemical and pharmaceutical industry and specifically to an agent which is 8-(methoxycarbonyl)-4b,8-dimethyl-3-(2-methylpropanoyl)-tetradecahydrophenanthrene-1,2,10a-tricarboxylic acid of formula (I): , having low toxicity and marked anti-inflammatory and anti-ulcer activity. Described also is a method of producing 8-(methoxycarbonyl)-4b,8-dimethyl-3-(2-methylpropanoyl)-tetradecahydrophenanthrene-1,2,10a-tricarboxylic acid involving reaction of methyl ether of maleopimaric acid with ozone in methylene chloride medium at temperature 0C with output of 89% after re-crystallisation. ^ EFFECT: improved properties of compounds. ^ 2 cl, 2 ex, 2 tbl