PREPARATION AND/OR PURIFICATION OF OLIGONUCLEOTIDE CONJUGATES
摘要
<p>Methods, systems and/or kits for the preparation, purification and isolation of oligonucleotide conjugates, comprising conjugation of modified antibodies or proteins with at least one modified oligonucleotide at greater than 80% efficiency to form oligonucleotide conjugates and isolating the oligonucleotide conjugates from the conjugation solution by binding the conjugates to an immobilized binder, wherein the binder may be a metal ion or an antibody.</p>
申请公布号
WO2011100493(A1)
申请公布日期
2011.08.18
申请号
WO2011US24439
申请日期
2011.02.11
申请人
SOLULINK, INC.;SCHWARTZ, DAVID, A.;MENDOZA, LEOPOLDO, G.