发明名称 |
TRANSGENIC MOUSE FOR SCREENING AND FOR STUDIES OF THE PHARMACODYNAMICS AND PHARMACOKINETICS OF LIGANDS ACTING ON THE OESTROGEN RECEPTOR AND ITS INTRACELLULAR RECEPTORS, AND METHOD FOR THE PREPARATION THEREOF |
摘要 |
The object of the invention is a method for the production of a non-human transgenic mammal by means of which it is possible to monitor in vivo and in all the tissues the state of activation of any intracellular receptor, utilising a reporter gene inducible by natural or synthetic molecules which modulate the activity of such receptor. The mammal is question is preferably a mouse.
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申请公布号 |
US2011203008(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
US201113076807 |
申请日期 |
2011.03.31 |
申请人 |
T.O.P. (TRANSGENIC OPERATIVE PRODUCTS) S.R.L. |
发明人 |
MAGGI ADRIANA CATERINA;CIANA PAOLO |
分类号 |
G01N33/00;A01K67/027;C12N5/10;C12N15/85;G01N33/50 |
主分类号 |
G01N33/00 |
代理机构 |
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主权项 |
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地址 |
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