COATED SLIDE

摘要

A single layer multi-silane coating construct displays controlled covalent attachment between biological materials and microscope slide substrates. Choice of various silanation reagents and their mix ratios provides control over the overall hydrophilic/hydrophobic surface behavior, attachment site density, and reactive moiety type. Both two-dimensional (2d) and three-dimensional (3d) configurations use the same foundation basics. Improved biological adhesion and fluid flow during subsequent processing is achieved. The 3d configuration offers conformal adhesion for those tissue materials that are not monotonically flat as well as multiple point capture of protein/peptides.