发明名称 DIAZAINDOLE DERIVATIVES AND THEIR USE IN THE INHIBITION OF C-JUN N-TERMINAL KINASE
摘要 The invention relates to diazaindole derivatives represented by the general formula (I): where A, E, G, R1, R2, R3 and R4 are defined herein, or pharmaceutically acceptable salts thereof, their use in the inhibition of c-Jun N-terminal kinase (JNK) activity, their use in medicine and particularly in the treatment of neurodegenerative disorders, inflammatory diseases, autoimmune diseases and/or organ failure. The invention also provides processes for the manufacture of said diazaindole derivatives and compositions containing them.
申请公布号 US2011195951(A1) 申请公布日期 2011.08.11
申请号 US200913057448 申请日期 2009.07.28
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 GRACZYK PIOTR PAWEL;BHATIA GURPREET SINGH
分类号 A61K31/553;A61K31/437;A61K31/4985;A61K31/5025;A61K31/5377;A61P19/02;A61P25/00;A61P29/00;C07D413/14;C07D471/04;C07D487/04 主分类号 A61K31/553
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