发明名称 |
OPHTHALMIC COMPOSITION CAPABLE OF FORMING GEL |
摘要 |
Disclosed is a material for use in ophthalmologic organ replacement, which is transparent, has controllable physical properties, and can have physical properties suitable for use as an ophthalmic tissue when the hardness of a gel produced from the material or the fluidability of a sol produced from the material at a specific temperature or lower is varied. Specifically disclosed is an ophthalmologic composition capable of forming a gel, which comprises a polyethylene glycol that is represented by formula 1 and has one end modified with a long-chain alkyl group, a polyethylene glycol that is represented by formula 2 and has both ends modified with a long-chain alkyl group, and a solvent.
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒR 1 -O-(CH 2 CH 2 O-)n1-R 2 €ƒ€ƒ€ƒ€ƒ€ƒ(Formula 1)
[In formula 1, R 1 represents an alkyl group having 1 to 4 carbon atoms; R 2 represents an alkyl group having 16 to 22 carbon atoms; and n1 represents the average number of moles of added oxyethylene groups and falls within the range from 45 to 450.]
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒR 3 -O-(-CH 2 CH 2 O-)n2-R 4 €ƒ€ƒ€ƒ€ƒ€ƒ(Formula 2)
[In formula 2, R 3 and R 4 independently represents an alkyl group having 16 to 22 carbon atoms; and n2 represents average number of moles of added oxyethylene groups and falls within the range from 45 to 450.] |
申请公布号 |
EP2353620(A1) |
申请公布日期 |
2011.08.10 |
申请号 |
EP20090823328 |
申请日期 |
2009.10.29 |
申请人 |
HOYA CORPORATION;PUBLIC UNIVERSITY CORPORATION NARA MEDICAL UNIVERSITY;KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION |
发明人 |
YOKOYAMA, YUICHI;MATSUURA, TOYOAKI;HARA, YOSHIAKI;ANNAKA, MASAHIKO;MARUYAMA, KEIICHI;TANAKA, SUSUMU |
分类号 |
A61L27/00;A61F2/14;A61F2/16;A61L27/52 |
主分类号 |
A61L27/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|