摘要 |
<p><P>PROBLEM TO BE SOLVED: To obtain a protein by using dockerin-cohesin binding in a eukaryotic microorganism. <P>SOLUTION: There is disclosed a eukaryotic microorganism for producing a protein using dockerin-cohesin binding, wherein the eukaryotic microorganism has following characteristics: (a) one or more sugar chain modification-related genes selected from the group consisting of CAX4, ALG5, ALG3, ALG9, ALG12, ALG6, ALG8, DIE2, OST3, OST5, PMT1, PMT2, ANP1, MNN2 and MNN11 have been destroyed. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |