发明名称 TWO STAGE ENRICHMENT OF CELL-FREE FETAL DNA IN MATERNAL PLASMA
摘要 The present invention provides methods for enriching fetal nucleic acid in a biological sample from a maternal host. Also provided are methods for detecting the presence or absence of markers in fetal, tumor, or neoplastic nucleic acid. The methods can include treating the biological sample with DNase and, optionally, performing whole genome amplification on the treated samples. The biological sample can be, for example, a blood sample.
申请公布号 US2011183338(A1) 申请公布日期 2011.07.28
申请号 US20090865381 申请日期 2009.01.30
申请人 NOVARTIS VACCINES AND DIAGNOSTICS, INC. 发明人 BISCHOFF FARIDEH
分类号 C12Q1/68;C07H21/00;C12N9/16;C12P19/34 主分类号 C12Q1/68
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