| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to a method of producing a ketazine compound of formula (1) from a ketone compound of formula (2), ammonia and an oxidising agent, where a solution containing a ketone compound of formula (2) and ammonia is brought into contact with aqueous solution of sodium hypochlorite or hydrogen peroxide in a tubular reactor, having flow channel width between 2 and 10000 mcm where R1 and R2 are identical or different and each denotes a C1-6 alkyl group, or R1 and R2 are bonded to form a C2-7alkylene group with a straight chain where R1 and R2 are as described above and each of the liquids is in laminar flow state. ^ EFFECT: obtaining ketazine compounds with high output and with inhibition of by-products. ^ 4 cl, 1 tbl, 2 ex, 2 dwg |
