发明名称 |
BMP-7 VARIANTS WITH REDUCED IMMUNOGENICITY |
摘要 |
The invention is directed to bone morphogenetic proteins that have reduced immunogenicity. In particular, the invention is directed to human BMP-7 that has been modified to reduce immunogenicity through alteration of the amino acid sequence of wild-type BMP-7.
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申请公布号 |
CA2785038(A1) |
申请公布日期 |
2011.07.21 |
申请号 |
CA20102785038 |
申请日期 |
2010.12.21 |
申请人 |
STRYKER CORPORATION |
发明人 |
PATTERSON, MARILYN ELIZABETH;ALAOUI-ISMAILI, MOULAY HICHAM |
分类号 |
C07K14/51;A61K38/18 |
主分类号 |
C07K14/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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