发明名称 |
siRNA SILENCING OF FILOVIRUS GENE EXPRESSION |
摘要 |
The present invention provides siRNA molecules that target Filovirus gene expression and methods of using such siRNA molecules to silence Filovirus gene expression. The present invention also provides nucleic acid-lipid particles that target Filovirus gene expression comprising an siRNA that silences Filovirus gene expression, a cationic lipid, and a non-cationic lipid.
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申请公布号 |
US2011177131(A1) |
申请公布日期 |
2011.07.21 |
申请号 |
US20100878946 |
申请日期 |
2010.09.09 |
申请人 |
PROTIVA BIOTHERAPEUTICS, INC. |
发明人 |
MACLACHLAN IAN;SOOD VANDANA;GEISBERT THOMAS W.;HENSLEY LISA E.;KAGAN ELLIOTT |
分类号 |
A61K31/713;A61K9/00;A61P31/14;B82Y5/00;C07H21/02;C12N15/113 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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