IL-17 receptor A antigen binding proteins

摘要

The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL- 17 Receptor 5 A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-I 7R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL 17RA neutralizing antibodies described herein.