| 摘要 |
PROBLEM TO BE SOLVED: To provide a use of cholesterol-lowering agent, more specifically a use of particular dosages or dosage ranges of an HMG CoA reductase inhibitor. SOLUTION: The invention concerns the use of particular oral dosages or dosage ranges of the compound (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically acceptable salt thereof, to alter beneficially lipid levels or lipid ratios in a human patient in need thereof, as well as pharmaceutical compositions of the compound or salts adapted for oral administration which comprise such dosages, and methods of preparation thereof. COPYRIGHT: (C)2011,JPO&INPIT |
