| 摘要 |
PROBLEM TO BE SOLVED: To provide a new device for predicting the expression in colon bacillus expression system. SOLUTION: The expression-predicting device 1 is equipped with a statistical model-memorizing part 18 for memorizing a statistical model for determining whether the formed gene is expressed or not by mechanically studying the results of expression experiments of DNA sequences by using (1) codons contained in the DNA sequence, (2) the continuing number of continuing prescribed amino acids in the amino acid sequence of an expressing protein from the DNA sequence, (3) the continuing number of continuing amino acids exhibiting prescribed physical characteristics or chemical characteristics, (4) the number, length or proportion of disorder regions, (5) the number of transmembrane regions, and (6) the number of amino acids in the surface residual group, as parameters, a DNA sequence-inputting part 10 for inputting the DNA sequence, a parameter value-calculating part 12 for calculating the values of the parameters of (1) to (6) from the inputted DNA sequence, an expression-determining part 16 for determining whether the DNA sequence is expressed or not by applying the values of the parameters to the statistical model, and a result-outputting part 20 for outputting the determined result. COPYRIGHT: (C)2011,JPO&INPIT |
