发明名称 NICOTINE IMMONONANOTHERAPEUTICS
摘要 The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. For example, the present invention nanocarriers capable of eliciting an immune response and the production of anti-nicotine antibodies.
申请公布号 KR20110074903(A) 申请公布日期 2011.07.04
申请号 KR20117010819 申请日期 2009.10.09
申请人 MASSACHUSETTS INSTITUTE OF TECHNOLOGY;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 发明人 IANNACONE MATTEO;VON ANDRIAN ULRICH;FAROKHZAD OMID C.;ALEXIS FRANK;BASTO PAMELA;SHI JINJUN;MOSEMAN ELLIOTT ASHLEY;LANGER ROBERT;TONTI ELENA
分类号 A61K39/395;A61K9/48;A61K47/48;A61P35/00 主分类号 A61K39/395
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