| 发明名称 |
NOVEL 1-BENZYL-3-HYDROXYMETHYLINDAZOLE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1, CX3CR1 AND P40 |
| 摘要 |
The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40, and to their use in a method for treating or preventing diseases based on the expression of MCP-1, CX3CR1 and p40.
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| 申请公布号 |
US2011160205(A1) |
申请公布日期 |
2011.06.30 |
| 申请号 |
US201113041557 |
申请日期 |
2011.03.07 |
| 申请人 |
AZIENDE CHIM. RIUN. ANG. FRANC. A.C.R.A.F. S.P.A. |
发明人 |
GUGLIELMOTTI ANGELO;FURLOTTI GUIDO;MANGANO GIORGINA;CAZZOLLA NICOLA;GAROFALO BARBARA |
| 分类号 |
A61K31/5377;A61K31/416;A61K31/4439;A61K31/496;A61P1/00;A61P3/00;A61P3/04;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P25/28;A61P29/00;A61P31/12;A61P35/00;A61P35/04;A61P37/06 |
主分类号 |
A61K31/5377 |
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