发明名称 ANTI-FLT3 ANTIBODIES AND METHODS OF USING THE SAME
摘要 <p>The present invention relates to anti-FLT3 antibodies with a modified Fc region comprising the amino acid substitututions 239D and 332E to enhance antibody- dependent cell cytotoxicity (ADCC) of these antibodies. The invention further relates to pharmaceutical compositions containing these antibodies, nucleic acids encoding these antibodies as well as methods of using such antibodies.</p>
申请公布号 WO2011076922(A1) 申请公布日期 2011.06.30
申请号 WO2010EP70659 申请日期 2010.12.23
申请人 SYNIMMUNE GMBH;GROSSE-HOVEST, LUDGER;BUEHRING, HANS-JOERG;HOFMANN, MARTIN;AULWURM, STEFFEN;JUNG, GRUNDRAM 发明人 GROSSE-HOVEST, LUDGER;BUEHRING, HANS-JOERG;HOFMANN, MARTIN;AULWURM, STEFFEN;JUNG, GRUNDRAM
分类号 C07K16/28;A61K39/395;A61P35/00;A61P35/02 主分类号 C07K16/28
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