发明名称 Methods For Selectively Modulating Survivin Apoptosis Pathways
摘要 The present invention, based on the discovery of a new biological phenomena, provides methods and compositions for use in identifying agents that modulate the phosphorylation of survivin, the interaction between survivin and p34cdc2-cyclin B1 kinase complex, and the interaction between survivin and caspase-9. Related methods and compositions can be used to modulate survivin regulated apoptosis.
申请公布号 US2011160278(A1) 申请公布日期 2011.06.30
申请号 US20090469122 申请日期 2009.05.20
申请人 ALTIERI DARIO C 发明人 ALTIERI DARIO C.
分类号 A61K31/7088;A61K31/711;A61K38/00;A61K45/00;A61K48/00;A61P35/00;A61P43/00;C07K16/18;C12N1/00;C12N5/09;C12Q1/02;C12Q1/48;G01N33/15;G01N33/50;G01N33/53;G01N33/573 主分类号 A61K31/7088
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