| 发明名称 |
METHODS FOR LOWERING SERUM CHOLESTEROL IN A SUBJECT USING INHIBITION OF PCSK9 |
| 摘要 |
<p>The invention relates to a method of lowering serum cholesterol using a double- stranded ribonucleic acid (dsRNA) for inhibiting the expression of the PCSK9 gene (PCSK9 gene) and an antigen binding protein (ABP) that binds to and inhibits a PCSK9 protein. Also provided are methods of treating or preventing conditions associated with elevated serum cholesterol using the dsRNAs and ABPs of the invention.</p> |
| 申请公布号 |
WO2011028938(A8) |
申请公布日期 |
2011.06.30 |
| 申请号 |
WO2010US47726 |
申请日期 |
2010.09.02 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC.;RHODES, JASON |
发明人 |
RHODES, JASON |
| 分类号 |
A61K31/7105;A61K39/395;C07H21/02 |
主分类号 |
A61K31/7105 |
| 代理机构 |
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