发明名称 |
Multiple-variable dose regimen for treating TNF-alpha-related disorders |
摘要 |
Multiple-variable dose methods for treating TNFalpha-related disorders, including Crohn's disease and psoriasis, comprising administering TNFalpha inhibitors, including TNFalpha antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase. |
申请公布号 |
EP2338516(A2) |
申请公布日期 |
2011.06.29 |
申请号 |
EP20100196132 |
申请日期 |
2005.04.11 |
申请人 |
ABBOTT BIOTECHNOLOGY LTD |
发明人 |
HOFFMAN, REBECA S.;CHARTASH, ELLIOT;TAYLOR, LORI K.;GRANNEMAN, GEORGE RICHARD;YAN, PHILIP |
分类号 |
A61K39/40;A61K38/00;A61K39/395;A61P17/06;A61P37/00;A61P37/06;C07K16/24 |
主分类号 |
A61K39/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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