发明名称 |
Use of molecular chaperones for the enhanced production of secreted, recombinant proteins in mammalian cells |
摘要 |
The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by co-expressing at least one chaperone protein. |
申请公布号 |
EP2338911(A1) |
申请公布日期 |
2011.06.29 |
申请号 |
EP20100013146 |
申请日期 |
2004.03.16 |
申请人 |
BAYER PHARMACEUTICALS CORPORATION |
发明人 |
CHAN, SHAM-YUEN;TANG, HSINYJ YVETTE;TAO, YIWEN;WU, YONGJIAN;KELLY, RUTH |
分类号 |
C07K14/755;C07K14/81;C12N5/00;C12N15/85;C12P21/00 |
主分类号 |
C07K14/755 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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