发明名称 WHOLE BLOOD THROMBINE ACTIVITY TEST
摘要 FIELD: medicine. ^ SUBSTANCE: for thrombin production measurement, a layer of said sample contacts with a fluorogenic substratum of thrombin where the thickness of said layer is 0.05 to 5 mm, while the surface area is 10 to 500 mm2. Further, the thrombin production environment in said sample is provided. It is followed by measuring the fluorescence emitted from the layer surface by a fluorescent group released by the fluorescent substratum as a result of an enzymatic action of produced thrombin on said fluorogenic substratum. Besides, the invention ensures a kit for measuring the thrombin activity in the sample. ^ EFFECT: higher measuring accuracy. ^ 29 cl, 12 dwg, 5 ex
申请公布号 RU2422835(C2) 申请公布日期 2011.06.27
申请号 RU20070137972 申请日期 2006.04.26
申请人 SINAPS B.V. 发明人 KHEMKER KHENDRIK KOENRAD;BEGUIN S'JUZET;AL'-DIERI RAED;VAGENVURD ROBERT;NIZHUIS SABASTIAN;GISEN PITER
分类号 C12Q1/56;G01N33/86 主分类号 C12Q1/56
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