发明名称 |
Inhibition of factor B, the alternative complement pathway and methods related thereto |
摘要 |
<p>Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such inhibitors to reduce or prevent airway hyperresponsiveness and/or airway inflammation by selectively inhibiting the alternative complement pathway, thereby treating diseases in which such conditions play a role. Also disclosed is the use of such inhibitors to reduce or prevent other diseases and conditions, including ischemia-reperfusion injury, by inhibition of the alternative complement pathway.</p> |
申请公布号 |
AU2005212369(B2) |
申请公布日期 |
2011.06.23 |
申请号 |
AU20050212369 |
申请日期 |
2005.02.10 |
申请人 |
MEDICAL UNIVERSITY OF SOUTH CAROLINA FOUNDATION FOR RESEARCH DEVELOPMENT;NATIONAL JEWISH MEDICAL AND RESEARCH CENTER;THE REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
GELFAND, ERWIN W.;HOLERS, VERNON MICHAEL;GILKESON, GARY STEVEN;THURMAN, JOSHUA M.;TAUBE, CHRISTIAN |
分类号 |
C07K16/40;A61K39/395;C12P21/08 |
主分类号 |
C07K16/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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