| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a combination or multivalent vaccine comprising acellular vaccine components, and to provide use thereof. <P>SOLUTION: There is provided a multivalent immunogenic component for conferring protective in a host against disease caused by infection with Bordetella pertussis, Clostridium tetani, Corynebacterium diphtheriae and/or Haemophilus influenzae, comprising: (a) pertussis toxoid, filamentous haemagglutinin, pertactin and agglutinogens in purified form; (b) tetanus toxoid; (c) diphtheria toxoid; and, (d) a conjugate of a carrier molecule selected from tetanus toxoid and diphtheria toxoid and a capsular polysaccharide of Haemophilus influenzae type b. wherein the individual components of the preparation are adjusted such that the immunogenicity of individual components is not impaired by other individual components of the preparation. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
