发明名称 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY
摘要 The present invention relates to compounds of Formula (I), below, (wherein R1, R2, R3, R27, R28, R29, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity.
申请公布号 US2011150757(A1) 申请公布日期 2011.06.23
申请号 US20080738529 申请日期 2008.10.16
申请人 SIDDIQUI M ARSHAD;DAI CHAOYANG;MANSOOR UMAR FARUK;YANG LIPING;VITHARANA LALALNTHI DILRUKSHI;ANGELES ANGIE R 发明人 SIDDIQUI M. ARSHAD;DAI CHAOYANG;MANSOOR UMAR FARUK;YANG LIPING;VITHARANA LALALNTHI DILRUKSHI;ANGELES ANGIE R.
分类号 A61K31/403;A61K31/407;A61K31/438;A61K31/454;A61K31/7105;A61K31/711;A61K38/21;A61K39/395;A61K51/00;A61P1/00;A61P9/00;A61P19/02;A61P29/00;A61P31/10;A61P35/00;A61P35/02;A61P37/02;A61P37/06;C07D209/96;C07D401/12;C07D471/10;C07D491/107 主分类号 A61K31/403
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