| 发明名称 |
MODULATION OF SMRT EXPRESSION |
| 摘要 |
Disclosed herein are compounds and methods for decreasing SMRT and treating metabolic and/or cardiovascular diseases in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to SMRT include obesity, diabetes, dyslipidemia, and hypothyroidism.
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| 申请公布号 |
US2011152351(A1) |
申请公布日期 |
2011.06.23 |
| 申请号 |
US20090993249 |
申请日期 |
2009.05.21 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
PANDEY SANJAY K.;BHANOT SANJAY;MARCUSSON ERIC G.;FREIER SUSAN M. |
| 分类号 |
A61K31/7088;A61P3/04;A61P3/06;A61P3/10;A61P5/16;A61P5/50 |
主分类号 |
A61K31/7088 |
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