发明名称 |
A stabilized polymeric delivery system |
摘要 |
The invention relates to a delivery system for the sustained and controlled delivery of a group of bioactive agents. More particularly, the invention relates to a delivery system and a method for delivery of a bioactive agent containing a nucleophilic functional group by means of a biodegradable, sustained-release implant. The implant may be a preformed implant, microparticles or an formed implant. The implant includes a biodegradable thermoplastic polymer, the bioactive agent having a nucleophilic group substituent and a stabilizing associate as well as other optional components. The combination of the stabilizing associate with the bioactive agent prevents and/or minimizes and/or lessens degradation of the thermoplastic polymer by the bioactive agent. |
申请公布号 |
AU2005304435(A8) |
申请公布日期 |
2011.06.23 |
申请号 |
AU20050304435 |
申请日期 |
2005.11.10 |
申请人 |
TOLMAR THERAPEUTICS, INC. |
发明人 |
DADEY, ERIC;ZHOU, MINGXING |
分类号 |
A61K9/14 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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