| 发明名称 |
USE OF FURFURAL DERIVATIVES AS ANTI-SICKLING AGENTS |
| 摘要 |
<p>The invention provides the use of a compound for the treatment of sickle cell disease. The compound has the structure: (see formula I) wherein R1 is CHO, or an aldehyde protecting group selected from the group consisting of: (see formula II) and (see formula III) n=0-4, and R2 is selected from the group consisting of hydroxymethyl, ethyl and methyl.</p> |
| 申请公布号 |
CA2507545(C) |
申请公布日期 |
2011.06.21 |
| 申请号 |
CA20032507545 |
申请日期 |
2003.12.03 |
| 申请人 |
VIRGINIA COMMONWEALTH UNIVERSITY |
发明人 |
SAFO, MARTIN K.;DANSO-DANQUAH, RICHMOND;NOKURI, SAMUEL;MUSAYEV, FAIK N.;JOSHI, GAJANAN S.;BURNETT, JAMES C.;ABRAHAM, DONALD J. |
| 分类号 |
C07D417/04;A61K31/34;A61K31/381;A61K31/40;A61K31/401;A61K31/66;C07D207/30;C07D307/34;C07D409/04 |
主分类号 |
C07D417/04 |
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