发明名称 Aryl alkyl sulfonamides as therapeutic agents for the treatment of bone conditions
摘要 The present invention pertains to compounds of the following formula (wherein RP, r, q, RN, Ralk, and Q are as defined herein) and compositions comprising those compounds. The compounds may be used to inhibit osteoclast survival, formation, and/or activity; to inhibit conditions mediated by osteoclasts and/or characterised by bone resorption; in the treatment of bone disorders such as osteoporosis, rheumatoid arthritis, cancer associated bone disease, Paget's disease; and/or in the treatment of conditions associated with inflammation or activation of the immune system.
申请公布号 US7964643(B2) 申请公布日期 2011.06.21
申请号 US20050628084 申请日期 2005.05.23
申请人 THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN 发明人 RALSTON STUART HAMILTON;GREIG IAIN ROBERT;MOHAMED AYMEN IBRAHIM IDRIS;VAN 'T HOF ROBERT JURGEN
分类号 A61K31/18;C07C311/00;C07C311/17;C07C311/18;C07C311/29;C07C311/40;C07C311/46;C07C323/67;C07F7/18 主分类号 A61K31/18
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