摘要 |
Provided are compositions and methods useful for modulation of signaling through the Toll- like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease. |
申请人 |
VENTIRX PHARMACEUTICALS, INC.;ARRAY BIOPHARMA, INC;HOWBERT, JAMES, JEFFRY;DIETSCH, GREGORY;HERSHBERG, ROBERT;BURGESS, LAURENCE, E.;DOHERTY, GEORGE, A.;EARY, C. TODD;GRONEBERG, ROBERT, D.;JONES, ZACHARY |
发明人 |
HOWBERT, JAMES, JEFFRY;DIETSCH, GREGORY;HERSHBERG, ROBERT;BURGESS, LAURENCE, E.;DOHERTY, GEORGE, A.;EARY, C. TODD;GRONEBERG, ROBERT, D.;JONES, ZACHARY |