发明名称 1,1,1-trifluor-2-hydroxy-3-phenylpropanderivater
摘要 The present invention relates to compounds of formula I wherein A, n, R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
申请公布号 DK2205562(T3) 申请公布日期 2011.06.14
申请号 DK20080804354T 申请日期 2008.09.18
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BAILLY, JACQUES;HERTEL, CORNELIA;HUNZIKER, DANIEL;LERNER, CHRISTIAN;OBST SANDER, ULRIKE;PETERS, JENS-UWE;PFLIEGER, PHILIPPE;SCHULZ-GASCH, TANJA
分类号 C07D213/30;A61K31/44;A61P3/00;A61P9/00;C07D215/14;C07D217/16;C07D231/12;C07D233/64;C07D237/08;C07D239/26;C07D241/12;C07D277/24;C07D277/62;C07D401/06;C07D471/04 主分类号 C07D213/30
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