发明名称 |
TREATMENT OF NERVE INJURIES |
摘要 |
This invention relates to treatment of nerve injuries and regeneration of nerves and nerve function in the acutely and chronically lesioned central and peripheral nervous system. The invention provides a pharmaceutical composition comprising histone, e.g., H1. It was surprisingly shown that histones, in particular histone Hl, can be used for the preparation of a pharmaceutical composition for treatment and/or prevention of acute and chronic injuries to the central and peripheral nervous system, for promoting growth and/or regrowth of nerves and enhancing formation of synapses and synaptic plasticity, and for neuroprotection. |
申请公布号 |
WO2011063989(A2) |
申请公布日期 |
2011.06.03 |
申请号 |
WO2010EP07265 |
申请日期 |
2010.11.30 |
申请人 |
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF;SCHACHNER, MELITTA;KLEENE, RALF;MISHRA, BIBHIDATTA |
发明人 |
SCHACHNER, MELITTA;KLEENE, RALF;MISHRA, BIBHIDATTA |
分类号 |
A61K38/17;A61P25/00 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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地址 |
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