发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING MIRNA-100 AND ITS USE IN THE MODULATION OF BLOOD VESSEL GROWTH AND ENDOTHELIAL INFLAMMATION |
摘要 |
Disclosed is a pharmaceutical composition comprising a miRNA-100 molecule or an antagomir thereof or a variant thereof for use as a medicament for the positive or negative modulation of blood vessel growth and vascular inflammation wherein the miRNA-100 or the miRNA antagomir has a homology of at least 85% to any of SEQ ID NO:1, 2, 3 and/or 9. |
申请公布号 |
CA2782026(A1) |
申请公布日期 |
2011.06.03 |
申请号 |
CA20102782026 |
申请日期 |
2010.11.18 |
申请人 |
UNIVERSITAETSKLINIKUM FREIBURG |
发明人 |
GRUNDMANN, SEBASTIAN;MOSER, MARTIN;BODE, CHRISTOPH;BLUHM, FRANZISKA;HANS, FELIX |
分类号 |
C12N15/113;A61K31/711;A61K31/713;A61P9/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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