| 摘要 |
<p>Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, Metabolic Syndrome, obesity, hypercholesterolemia, and hypertension.</p> |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
DANG, QUN;BAO, JIANMING;JIANG, JINLONG;LU, HUAGANG;BOOKSER, BRETT C.;GIBSON, TONY S.;JIANG, HONGJIAN;CHUNG, DE MICHAEL;KASSICK, ANDY;KEKEC, AHMET;LAN, PING;MAKARA, GERGELY M.;ROMERO, F. ANTHONY;SEBHAT, IYASSU;WILSON, DAVID;WODKA, DARIUSZ |
