Micro-RNA and tissue repair

摘要

The present invention relates to the use of miR-126 in postnatal tissue repair. In particular, the isolated nucleic acids comprising the miR-126 nucleic acid sequence are useful in the prophylaxis or treatment of atherosclerosis as well as for the prophylaxis or treatment of tissue damages resulting in or due to various arterial based diseases. In a further aspect, the present invention relates to the use of nucleic acids comprising the miR-126 nucleic acid sequence for the recruitment of progenitor cells to tissue, in particular, blood vessels.