发明名称 |
KONJUGATE ZUR ZUFÜHRUNG AN KNOCHEN UND VERFAHREN ZU DEREN VERWENDUNG BEIM HINFÜHREN VON PROTEINEN ZUM KNOCHEN |
摘要 |
A bone delivery conjugate having a structure selected from the group consisting of :A) X-D n -Y-protein-Z; and B) Z-protein-Y- D n -X, wherein X is absent or is an amino acid sequence of at least one amino acid; Y is absent or is an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; and D n is a poly aspartate wherein n = 10 to 16. Compositions comprising same and uses thereof. |
申请公布号 |
DE602005027461(D1) |
申请公布日期 |
2011.05.26 |
申请号 |
DE20056027461T |
申请日期 |
2005.04.21 |
申请人 |
ENOBIA PHARMA INC. |
发明人 |
CRINE, PHILIPPE;BOILEAU, GUY;LEMIRE, ISABELLE;LOISEL, THOMAS P. |
分类号 |
C12N15/57;A61K38/46;A61K38/48;A61K47/48;A61P19/08;C12N9/14;C12N9/16;C12N9/50;C12N9/64;C12N15/55;G01N33/68 |
主分类号 |
C12N15/57 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|