发明名称 ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS
摘要 The invention relates to dimeric aryl-sulphonamido compounds endowed with inhibitory activity against metalloproteases MMP, having formula (I) below (M)-L-(M′) (I), wherein M and M′, the same or different from each other, represent the residues of the metalloproteases inhibitors of formula (II), wherein R, R1, R2, R3, G and n have the meanings reported in the specification; the invention also refers to the process for their preparation, to pharmaceutical compositions comprising them and to their use as therapeutic agents, particularly in the treatment of degenerative disorders.
申请公布号 US2011124653(A1) 申请公布日期 2011.05.26
申请号 US200913054590 申请日期 2009.07.21
申请人 BRACCO IMAGING S.P.A. 发明人 ROSSELLO ARMANDO;NUTI ELISA;TUCCINARDI TIZIANO;ORLANDINI ELISABETTA
分类号 A61K31/497;A61K31/166;A61P9/10;A61P11/00;A61P19/02;A61P25/28;A61P35/00;C07C237/48;C07D241/04 主分类号 A61K31/497
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