发明名称 |
METHODS FOR MODULATING EXPRESSION OF RBP4 |
摘要 |
Methods are provided for modulating RBP4 by administering a RBP4-specific modulator. Also provided are methods for treating cardiovascular and metabolic disorders in a subject or delaying or preventing risk factors thereof through the modulation of RBP4. The present invention is also directed to methods of decreasing lipid levels in a subject or for preventing or delaying the onset of a rise in lipid levels in a subject, comprising administering to said subject a RBP4-specific inhibitor.
|
申请公布号 |
US2011123521(A1) |
申请公布日期 |
2011.05.26 |
申请号 |
US20090993250 |
申请日期 |
2009.05.21 |
申请人 |
ISIS PHARMACEUTICALS, INC |
发明人 |
MONIA BRETT P.;YU XING-XIAN;BHANOT SANJAY |
分类号 |
A61K39/395;A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K38/16;A61P3/04;A61P3/06;A61P3/08;A61P9/10 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|