发明名称 METHOD OF TREATING PROLIFERATIVE DISORDERS AND OTHER PATHOLOGICAL CONDITIONS MEDIATED BY BCR-ABL, C-KIT, DDR1, DDR2 OR PDGF-R KINASE ACTIVITY
摘要 The present invention relates to a regimen for the administration of a pyrimidyl- aminobenzamide of formula (I) wherein the radicals as defined herein, or of a pharmaceutically acceptable salt thereof, for the treatment of proliferative disorders, particularly solid and liquid tumors, and other pathological conditions mediated by the Bcr-Abl oncoprotein, the cell transmembrane tyrosine kinase receptor c-Kit, DDR1 (discoidin domain receptor 1), DDR2 (discoidin domain receptor 2) or PDGF-R (platelet derived growth factor receptor) kinase activity, wherein the pyrimidylaminobenzamide of formula I and, optionally, pharmaceutically acceptable carriers, are dispersed in a fruit preparation.
申请公布号 WO2011062927(A1) 申请公布日期 2011.05.26
申请号 WO2010US56926 申请日期 2010.11.17
申请人 NOVARTIS AG;GALLAGHER, NEIL;YIN, OPHELIA 发明人 GALLAGHER, NEIL;YIN, OPHELIA
分类号 A61K31/506;A61K9/00;A61P35/00 主分类号 A61K31/506
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