发明名称 |
METHOD OF TREATING PROLIFERATIVE DISORDERS AND OTHER PATHOLOGICAL CONDITIONS MEDIATED BY BCR-ABL, C-KIT, DDR1, DDR2 OR PDGF-R KINASE ACTIVITY |
摘要 |
The present invention relates to a regimen for the administration of a pyrimidyl- aminobenzamide of formula (I) wherein the radicals as defined herein, or of a pharmaceutically acceptable salt thereof, for the treatment of proliferative disorders, particularly solid and liquid tumors, and other pathological conditions mediated by the Bcr-Abl oncoprotein, the cell transmembrane tyrosine kinase receptor c-Kit, DDR1 (discoidin domain receptor 1), DDR2 (discoidin domain receptor 2) or PDGF-R (platelet derived growth factor receptor) kinase activity, wherein the pyrimidylaminobenzamide of formula I and, optionally, pharmaceutically acceptable carriers, are dispersed in a fruit preparation. |
申请公布号 |
WO2011062927(A1) |
申请公布日期 |
2011.05.26 |
申请号 |
WO2010US56926 |
申请日期 |
2010.11.17 |
申请人 |
NOVARTIS AG;GALLAGHER, NEIL;YIN, OPHELIA |
发明人 |
GALLAGHER, NEIL;YIN, OPHELIA |
分类号 |
A61K31/506;A61K9/00;A61P35/00 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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