发明名称 Chiral CIS-imidazolines
摘要 There are provided compounds of the formula or the pharmaceutically acceptable salts thereof, wherein X, Y, Z, V 3 , V 2 , R 1 , R 2 , R 3 , R 4 and R 5 are as herein described, processes for obtaining said compounds and pharmaceutical preparations containing them. These compounds are useful as anticancer agents, in particular as agents in the treatment of solid tumors.
申请公布号 EP2325180(A1) 申请公布日期 2011.05.25
申请号 EP20100175975 申请日期 2008.09.30
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BARTKOVITZ, DAVID JOSEPH;CAI, JIANPING;CHU, XIN-JIE;LI, HONGJU;LOVEY, ALLEN JOHN;VU, BINH THANH;ZHAO, CHUNLIN
分类号 C07D401/04;A61K31/454;A61P35/00;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D417/14 主分类号 C07D401/04
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